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Furthermore, by interfering with folate metabolism and the one-carbon cycle, B 12 deficiency raises homocysteine levels and risks of related health problems

If the shift is large enough relative to the native preference due to ligand repulsion and ligand field effects the complex will either adopt the ligand-preferred geometry or be distorted in the direction of the ligand-preferred geometry

Can I take oral B-vitamin pills instead of injections

Golbidi S, Badran M, Laher I (2011) Diabetes and alpha lipoic acid

If the reason is less clear, the care team may recommend review of symptoms, outside records, or broader follow-up before turning B12 into a repeating plan